• Introduction Researchers have long followed the strategy tha

  2019-05-24

  

  Introduction Researchers have long followed the strategy that in order to achieve a fuller understanding of the causes of disease and how they can be prevented, it is necessary to study the biochemical and physiological processes involved in the etiology of disease. As I have argued in previous pap

• The aim of this study was to determine the therapeutic

  2019-05-24

  

  The aim of this study was to determine the therapeutic relevance of blocking RANKL in Ewing\'s sarcoma by using OPG administered by non-viral gene transfer approaches in two models of human Ewing sarcoma in immunodeficient mice. OPG was administered using amphiphilic polymers constituted by blocks o

• mglur Introduction Osteosarcoma OS is the

  2019-05-24

  

  Introduction Osteosarcoma (OS) is the most common type of bone tumor occurred in adolescents and children [1]. OS is highly malignant and accounts for about half of bone sarcomas with high potential of metastasis [2]. Treatment for OS is mainly depended on surgical operation, assisted with chemothe

• p2y receptor Although a wealth of studies tracking

  2019-05-24

  

  Although a wealth of studies tracking ODA+ have been done, few have provided in-depth study of how ODA+ in reproductive, maternal, newborn, and child health affects health outcomes, and to what extent the long-term goal of donors has been achieved through aid programmes. This panel dataset opens the

• Because of the high amplitude of atrial signals atrial

  2019-05-24

  

  Because of the high amplitude of atrial signals, atrial sensitivity was decreased from 0.5mV to 0.7mV to 1.0mV. As the sensitivity decreased, atrial sensing was restored gradually. With the sensitivity of 1.0mV, normal atrial sensing with mode switching was restored completely. The sensitivity was p

• br Entrainment As the principles

  2019-05-24

  

  Entrainment As the principles of entrainment initially described by Waldo for atrial flutter could be fulfilled by scar-mediated VT, characterization of the reentrant circuit provided a central isthmus as a favorable target [33,34]. In the late 1980s, the collective descriptions of entrainment,

• br Materials and methods Fifteen

  2019-05-24

  

  Materials and methods Fifteen healthy adult men participated in this study. The left anterior chest area was subdivided into 15 regions based on 5 longitudinal points (from the second to the sixth intercostal spaces) and 3 lateral points (including the left sternal border, midclavicular line, and

• br The west African outbreak of Ebola virus

  2019-05-24

  

  The 2014–15 west African outbreak of Ebola virus disease is unprecedented in scale, especially in Sierra Leone, which as of May 15, 2015, had reported 8598 confirmed cases and 3538 confirmed Ebola-related deaths. Sierra Leone\'s response to this emergency has been compromised by a fragile health s

• These studies demonstrated that the levels

  2019-05-23

  

  These studies demonstrated that the levels of essential inositol phosphatase in healthy pregnant women were significantly different from those of the general population. There is a need to evaluate more pregnant women, especially from different races, for the purpose of establishing specific normat

• Self reported health SRH is

  2019-05-23

  

  Self-reported health (SRH) is considered to be a valuable source of data on various aspects of general health. In fact, it is one of the most widely used indicators of health status in survey research, and is recommended by the World Health Organization. SRH can be influenced by individual determina

• Currently we are unable to

  2019-05-23

  

  Currently, we are unable to fully understand the ibmx and distribution of the AT arising around the apex of the triangle of Koch. Koyama et al. closely studied the spatial and topographic variation in the distribution of this type of AT around the His-bundle [17]. As demonstrated in the present cas

• br Tanto en el cuerpo principal de la revista como

  2019-05-23

  

  Tanto en el cuerpo principal de la revista como en la sección de análisis de libros y revistas, aparecen artículos y notas de tenor necrológico, los cuales ofrecen una suerte de homenaje póstumo cdc42 inhibitor personajes que generalmente habían actuado en el terreno científico, filosófico o de ge

• Si consideramos el estado incipiente de la

  2019-05-23

  

  Si consideramos el estado incipiente de la discusión alrededor de este concepto emergente, veremos que un análisis cualitativo más detallado de los textos constitucionales resulta bastante prometedor. Bolivia En el caso boliviano, buen vivir aparece como parte esencial de la refundación del Esta

• Evidence based interventions that are theory driven and

  2019-05-23

  

  Evidence based interventions that are theory driven and accessible within the local culture are do-able and do not need to rely on imported interventions—especially when those are costly. Many bereaved children and youth reside in the KU-55933 and have little recourse to good psychosocial support,

• br Methods br Results br Discussion ICC represents an aggres

  2019-05-23

  

  Methods Results Discussion ICC represents an aggressive malignancy arising from the intrahepatic biliary tree. Recent years have seen a dramatic increase in the incidence of ICC, making it the second most common primary liver cancer. Prognosis of ICC remains poor, with 5-year OS rates rangi

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